Kumabhulogi namavidiyo adlule, sikhulume kakhulu ngamabhaktheriya biofilms noma ama-plaque biofilms, kodwa ayini ngempela ama-biofilms futhi akha kanjani?
Ngokuyisisekelo, ama-biofilms ayinqwaba yamabhaktheriya kanye nesikhunta esinamathela endaweni ethile ngokusebenzisa into efana neglue esebenza njengehange futhi ehlinzeka ngokuvikeleka endaweni ezungezile.Lokhu kuvumela amabhaktheriya kanye nesikhunta esivalelwe ngaphakathi kwawo ukuthi sikhule sibheke eceleni futhi sibheke phezulu.Amanye ama-microorganisms athintana nalesi sakhiwo esinamathelayo aphinde avalelwe efilimini ekhiqiza ama-biofilms amabhaktheriya amaningi kanye nezinhlobo zesikhunta ezihlangana zibe amakhulu namakhulu ezendlalelo.I-matrix efana neglue yenza ukwelapha lawa ma-biofilms kube nzima kakhulu ngoba ama-antimicrobial kanye nezici zokuzivikela ezibambayo azikwazi ukungena ekujuleni kulawa mafilimu okwenza lezi zinambuzane zimelane nokwelashwa okuningi.
Ama-biofilms asebenza kahle kangangokuthi akhuthaza ukubekezelelana kwama-antibiotic ngokuvikela amagciwane ngokomzimba.Angenza amabhaktheriya amelane nemithi elwa namagciwane izikhathi eziyi-1,000, izibulala-magciwane kanye namasosha omzimba futhi aqashelwa ososayensi abaningi njengenye yezimbangela eziphambili zokumelana nama-antibiotic emhlabeni jikelele.
Amafilimu e-biofilm angakheka kuzo zombili izindawo eziphilayo nezingaphili okuhlanganisa amazinyo (i-plaque ne-tartar), isikhumba (njengamanxeba ne-seborrheic dermatitis), izindlebe (i-otitis), izinsiza zokwelapha (njengama-catheter nama-endoscopes), osinki basekhishini kanye nezindawo zokubala, ukudla nokudla. imishini yokucubungula, izindawo zasesibhedlela, amapayipi nezihlungi ezikhungweni zokuhlanza amanzi nasezikhungweni zokulawula inqubo kawoyela, igesi kanye ne-petrochemical.
Akhiwa kanjani ama-biofilms?
Amagciwane kanye nesikhunta kuhlala kukhona emlonyeni futhi ahlala ezama ukuhlanganisa amazinyo ngokubambelela okuqinile kwento efana neglue okukhulunywe ngayo ngenhla.(Izinkanyezi ezibomvu neziluhlaza kulo mfanekiso zimelela amagciwane nesikhunta.)
Lawa magciwane kanye nesikhunta kudinga umthombo wokudla ukusiza ekukhuleni nasekuzinzeni kolwelwesi.Lokhu ngokuyinhloko kuvela kuma-ion ensimbi ngokwemvelo atholakala emlonyeni njengensimbi, i-calcium ne-magnesium, phakathi kwezinye izinto.(Amachashazi aluhlaza emfanekisweni amelela la ma-ion ensimbi.)
Amanye amabhaktheriya aqoqana kule ndawo ukuze akhe amakholoni amancane, futhi ayaqhubeka nokukhipha le nto enamathelayo njengongqimba oluvikelayo olunjenge-dome olukwazi ukunikeza isivikelo kumasosha omzimba aphethe, ama-antimicrobial kanye nezibulala-magciwane.(Izinkanyezi ezinsomi emfanekisweni zimelela ezinye izinhlobo zebhaktheriya kanti ungqimba oluluhlaza lumelela ukwakheka kwe-matrix ye-biofilm.)
Ngaphansi kwaleli filimu elinamathelayo le-biofilm, amagciwane kanye nesikhunta ziphindaphindeka ngokushesha ukuze kwakhiwe iqoqo elinezinhlangothi ezi-3, elinezingqimba eziningi ezaziwa ngokuthi i-dental plaque okuyifilimu ewugqinsi engamakhulu namakhulu ezindlalelo ezijulile.Uma i-biofilm ifinyelela isisindo esibucayi, ikhulula amagciwane athile ukuze aqale le nqubo efanayo yokwenza ikholoni kwezinye izindawo zamazinyo aqinile eqhubekisela phambili ukwakheka koqweqwe kuzo zonke izindawo zamazinyo.(Ungqimba oluluhlaza emfanekisweni lubonisa ifilimu ye-biofilm ishuba futhi ikhulisa izinyo.)
Ekugcineni ama- plaque biofilms, ehlangene namanye amaminerali emlonyeni aqala ukubala, awenze into eqine ngokwedlulele, emagebhugebhu, efana nethambo ebizwa ngokuthi i-calculus, noma i-tartar.(Lokhu kuboniswa emfanekisweni wohlaka lwefilimu ephuzi eduze komugqa ongezansi kwamazinyo.)
Amagciwane ayaqhubeka nokwakha izingqimba ze-plaque kanye ne-tartar engena ngaphansi kwe-gumline.Lokhu, kuhlangene nezinhlaka zokubala ezicijile, ezimangelengele kuyacasula futhi kunwaye izinsini ngaphansi koshingamu okungagcina kubangele isifo se-periodontitis.Uma ingelashwa, ingaba nomthelela ezifweni zesistimu ezithinta inhliziyo yesilwane sakho esifuywayo, isibindi nezinso.(Isendlalelo sefilimu ephuzi emfanekisweni simelela lonke icwecwe le-biofilm elibalwayo futhi likhule ngaphansi kwe-gumline.)
Ngokwesilinganiso seNational Institute of Health (NIH, USA), cishe amaphesenti angu-80 azo zonke izifo ezibangelwa amagciwane abangelwa ama-biofilms.
I-Kane Biotech igxile ekuthuthukisweni kobuchwepheshe nemikhiqizo ehlakaza ama-biofilms futhi ibulale amagciwane.Ukucekelwa phansi kwama-biofilms kuvumela ukuncipha okukhulu kokusetshenziswa kwama-antimicrobial futhi ngaleyo ndlela kubambe iqhaza ekusetshenzisweni okunobuhlakani nangempumelelo kwalezi ejenti zokwelapha.
Ubuchwepheshe obuthuthukiswe yi-Kane Biotech be-bluestem ne-silkstem bunomthelela omuhle empilweni yomuntu, yezilwane kanye nemvelo.
Isikhathi sokuthumela: Jul-10-2023